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1. (WO2015113110) A METHOD FOR THE PURIFICATION OF EYE LENS CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/113110    International Application No.:    PCT/AU2015/000046
Publication Date: 06.08.2015 International Filing Date: 29.01.2015
IPC:
C12N 5/071 (2010.01)
Applicants: UNIVERSITY OF WESTERN SYDNEY [AU/AU]; Locked Bag 1797 Penrith, New South Wales 2751 (AU)
Inventors: O'CONNOR, Michael; (AU).
MURPHY, Patricia; (AU)
Agent: FB RICE; Patent and Trade Mark Attorneys Level 23, 44 Market Street Sydney NSW 2000 (AU)
Priority Data:
2014900269 29.01.2014 AU
Title (EN) A METHOD FOR THE PURIFICATION OF EYE LENS CELLS
(FR) PROCÉDÉ DE PURIFICATION DE CELLULES DE CRISTALLIN
Abstract: front page image
(EN)There is provide a method for the purification of eye lens cells and/or progenitor cells thereof from a mixed population of cells, comprising isolating cells on the basis of outer cell membrane expression of at least one marker selected from the group consisting of ROR1, GPR161, CD81, ODZ3, SLC7A11, SLC16A1 and SLC23A2 from the mixed cell population, and collecting the isolated cells. There are also provided purified preparations of cells expressing one or more of cell surface markers ROR1, GPR161, CD81, ODZ3, SLC7A11, SLC16A1 and SLC23A2, and progeny of the purified cells, as well as lentoids and lens-like structures prepared from the purified cells or progeny thereof and methods for the provision of the lentoids and lens-like structures.
(FR)L'invention concerne un procédé de purification de cellules de cristallin et/ou de cellules progénitrices de ces dernières à partir d'une population mixte de cellules, comprenant l'isolement des cellules sur la base de l'expression par la membrane cellulaire externe d'au moins un marqueur choisi dans le groupe constitué par ROR1, GPR161, CD81, ODZ3, SLC7A11, SLC16A1 et SLC23A2 à partir de la population mixte de cellules, et le recueil des cellules isolées. L'invention concerne également des préparations purifiées de cellules exprimant un ou plusieurs des marqueurs de la surface cellulaire ROR1, GPR161, CD81, ODZ3, SLC7A11, SLC16A1 et SLC23A2, et de la descendance des cellules purifiées, ainsi que des structures lentoïdes et de type cristallin préparées à partir des cellules purifiées ou de la descendance de ces dernières et des procédés pour la fourniture des structures lentoïdes et de type cristallin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)