Processing

Please wait...

Settings

Settings

Goto Application

1. WO2015107140 - LIPOSOME-BASED IMMUNOTHERAPY

Publication Number WO/2015/107140
Publication Date 23.07.2015
International Application No. PCT/EP2015/050747
International Filing Date 16.01.2015
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 9/127 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61P 3/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
CPC
A61K 2039/577
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
57characterised by the type of response, e.g. Th1, Th2
577tolerising response
A61K 39/0008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
0005Vertebrate antigens
0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
A61K 9/127
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
Applicants
  • FUNDACIÓ INSTITUT D'INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL [ES]/[ES]
  • FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA [ES]/[ES]
  • INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS [ES]/[ES]
Inventors
  • MASPOCH COMAMALA, Daniel
  • CANO SARABIA, Antonia María
  • VIVES PI, Marta
  • PUJOL AUTONELL, Irma
  • VERDAGUER AUTONELL, Juan
Agents
  • ZBM PATENTS
Priority Data
14151629.417.01.2014EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) LIPOSOME-BASED IMMUNOTHERAPY
(FR) IMMUNOTHÉRAPIE REPOSANT SUR UN LIPOSOME
Abstract
(EN) The present invention provides a liposome encapsulating an autoantigen, wherein the liposome has a size comprised from 500 to 15000 nm and the liposome membrane comprises phosphatydilserine (PS) in an amount comprised from 10 to 40% by weight with respect to the total membrane liposomal composition. Pharmaceutical or veterinary compositions comprising a therapeutically effective amount of said liposome are also provided. Further, the invention provides liposomes and pharmaceutical or veterinary compositions as defined above for use as a medicament, particularly for the treatment of autoimmune diseases. Finally the present invention provides liposomes and pharmaceutical or veterinary compositions as defined above for use in the restoration of tolerance to self in a patient suffering from an autoimmune disease.
(FR) La présente invention concerne un liposome encapsulant un autoantigène, le liposome présentant une taille située dans la plage allant de 500 à 15 000 nm et la membrane liposomique comprenant de la phosphatydilsérine (PS) à raison de 10 à 40 % en poids par rapport à la composition liposomale membranaire totale. L'invention concerne également des compositions pharmaceutiques ou vétérinaires comprenant une quantité thérapeutiquement efficace dudit liposome. L'invention concerne en outre des liposomes et des compositions pharmaceutiques ou vétérinaires tels que définis dans la description destinés à être utilisés en tant que médicament, en particulier pour le traitement de maladies auto-immunes. L'invention concerne enfin des liposomes et des compositions pharmaceutiques ou vétérinaires tels que définis dans la description destinés à être utilisés dans la restauration de la tolérance au soi chez un patient atteint d'une maladie auto-immune.
Related patent documents
BR112016016356This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
CN201580007978.3This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
Latest bibliographic data on file with the International Bureau