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1. (WO2015097536) ANTI-VISTA ANTIBODIES AND FRAGMENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2015/097536 International Application No.: PCT/IB2014/002868
Publication Date: 02.07.2015 International Filing Date: 22.12.2014
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01) ,G01N 33/574 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants:
JANSSEN PHARMACEUTICA NV [BE/BE]; Turnhoutseweg 30 B-2340 Beerse, BE
Inventors:
SNYDER, Linda; US
POWERS, Gordon; US
Priority Data:
61/920,69524.12.2013US
62/085,08626.11.2014US
Title (EN) ANTI-VISTA ANTIBODIES AND FRAGMENTS
(FR) ANTICORPS ET FRAGMENTS ANTI-VISTA
Abstract:
(EN) The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of making and using same. Methods of use include methods of treatment of cancer, including leukemias, lymphomas, solid tumors and melanomas.
(FR) L'invention concerne de nouveaux anticorps et des fragments qui se lient à un suppresseur Ig à domaine V de l'activation lymphocytaire T (VISTA,), et des procédés de préparation et d'utilisation de ceux-ci. L'invention concerne également des méthodes de traitement du cancer, y compris les leucémies, les lymphomes, les tumeurs solides et les mélanomes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
UAa201607766CA2935378SG11201605200XEP3087098KR1020160124086EA201691323
JP2017502667US20170051061AU2014372309CN106661107VN49520MYPI 2016001169
PH1/2016/501244DOP2016000153BR112016014966ID2017/10948IN201617024776CR20160339
TH180320