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1. WO2015097233 - FGF-18 FORMULATION IN XYLOGLUCAN GELS

Publication Number WO/2015/097233
Publication Date 02.07.2015
International Application No. PCT/EP2014/079194
International Filing Date 23.12.2014
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
50
Materials characterised by their function or physical properties
52
Hydrogels or hydrocolloids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
02
for joint disorders, e.g. arthritis, arthrosis
A61K 38/18 (2006.01)
A61L 27/52 (2006.01)
A61K 9/00 (2006.01)
A61K 47/36 (2006.01)
A61P 19/02 (2006.01)
CPC
A61K 38/18
A61K 38/1825
A61K 47/02
A61K 47/36
A61K 9/00
A61K 9/0019
Applicants
  • ARES TRADING S.A [CH/CH]; Zone Industrielle de L'Ouriettaz CH-1170 Aubonne, CH
Inventors
  • LO PRESTI, Caterina; IT
  • BULONE, Donatella; IT
  • DISPENZA, Clelia; IT
Agents
  • MERCK SERONO S.A; Zone Industrielle de l'Ouriettaz CH-1170 Aubonne, CH
Priority Data
13199588.824.12.2013EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FGF-18 FORMULATION IN XYLOGLUCAN GELS
(FR) FORMULATION DE FGF-18 DANS DES GELS DE XYLOGLUCANE
Abstract
(EN)
The invention relates to the field of pharmaceutical formulations. More particularly it is directed to xyloglucan hydrogels comprising Fibroblast Growth Factor 18 (FGF-18) compound and to methods of producing such hydrogels. The hydrogels of the invention can be used, once formed in situ, for the treatment of cartilage disorders such as osteoarthritis or cartilage injury.
(FR)
L'invention concerne le domaine des formulations pharmaceutiques. Elle se rapporte en particulier à des hydrogels de xyloglucane comprenant un composé du facteur de croissance des fibroblastes 18 (FGF-18) et à des procédés de production desdits hydrogels. Les hydrogels selon l'invention peuvent être utilisés, après formation in situ, pour le traitement d'affections cartilagineuses telles que l'arthrose ou une lésion cartilagineuse.
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