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1. WO2015087097 - PHARMACEUTICAL COMPOSITION COMPRISING A RYANODINE RECEPTOR ANTAGONIST FOR FACILITATING WOUND HEALING

Publication Number WO/2015/087097
Publication Date 18.06.2015
International Application No. PCT/HU2014/000124
International Filing Date 12.12.2014
IPC
A61K 31/4178 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4178not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A61K 45/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 17/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
CPC
A61K 31/4178
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
41641,3-Diazoles
4178not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A61K 31/422
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
42Oxazoles
422not condensed and containing further heterocyclic rings
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
Applicants
  • SZEGEDI TUDOMÁNYEGYETEM [HU]/[HU]
Inventors
  • ERŐS, Gábor
  • DEGOVICS, Döníz
  • HARTMANN, Petra
  • KEMÉNY, Lajos
Agents
  • DANUBIA PATENT AND LAW OFFICE LLC
Priority Data
P130072012.12.2013HU
Publication Language English (en)
Filing Language Hungarian (HU)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION COMPRISING A RYANODINE RECEPTOR ANTAGONIST FOR FACILITATING WOUND HEALING
(FR) COMPOSITIONS PHARMACEUTIQUES FACILITANT LA CICATRISATION
Abstract
(EN) The invention relates to the use of pharmaceutical compositions containing as the active agent a compound of formula I in the treatment of dermal wounds. The compositions may be used for the promotion of healing of wounds affecting the deeper layers under the epithelium, including dermal- and sub dermal connective tissue, being cut, punctured, sliced wounds or originating in insufficient tissue perfusion, chronic diseases or other harms. The compositions are formulated for local application and may comprise other active agents contributing to wound healing in addition to a compound of formula (I).
(FR) L'invention concerne l'utilisation de compositions pharmaceutiques contenant, en tant que principe actif, un composé de formule I, dans le traitement de lésions du derme. Lesdites compositions peuvent être utilisées pour favoriser la cicatrisation de blessures affectant les couches profondes sous l'épithélium, y compris le tissu conjonctif dermique et sous-cutané, qu'il s'agisse de coupure, de piqûre, de lacération, ou de blessures dues à une perfusion tissulaire insuffisante, à des maladies chroniques ou à d'autres maux. Ces compositions sont formulées pour une application locale et peuvent comprendre d'autres principes actifs contribuant à la cicatrisation en sus d'un composé de formule (I).
Latest bibliographic data on file with the International Bureau