WO2015069742 TISSUE ARRAY FOR CELL SPHEROIDS AND METHODS OF USE

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Publication Number WO/2015/069742

Publication Date 14.05.2015

International Application No. PCT/US2014/064091

International Filing Date 05.11.2014

IPC

CPC

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Applicants

THE JOHNS HOPKINS UNIVERSITY [US]/[US]

Inventors

BEACHLEY, Vince
ELISSEEFF, Jennifer, H.

Agents

DOERING, Andrea

Priority Data

61/900,090

05.11.2013

Publication Language English (en)

Filing Language English (EN)

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Title

(EN) TISSUE ARRAY FOR CELL SPHEROIDS AND METHODS OF USE

(FR) RÉSEAU TISSULAIRE POUR SPHÉROÏDES CELLULAIRES ET PROCÉDÉS D'UTILISATION

Abstract

(EN) The present invention generally features methods of preparing a microarray of cell spheroids, methods of preparing a micromold for embedding spheroids for histology, and methods of screening a library of agents.

(FR) La présente invention concerne d'une manière générale des procédés de préparation d'un microréseau de sphéroïdes cellulaires, des procédés de préparation d'une micromoule pour incorporer des sphéroïdes en vue d'une analyse histologique, et des procédés de criblage d'une bibliothèque d'agents.

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5	Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07	Animal cells or tissues

C	CHEMISTRY; METALLURGY
40	COMBINATORIAL TECHNOLOGY
B	COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
40	Libraries per se, e.g. arrays, mixtures
02	Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5	Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07	Animal cells or tissues

C	CHEMISTRY; METALLURGY
40	COMBINATORIAL TECHNOLOGY
B	COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
40	Libraries per se, e.g. arrays, mixtures
02	Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2503	Use of cells in diagnostics

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1. WO2015069742 - TISSUE ARRAY FOR CELL SPHEROIDS AND METHODS OF USE

G	PHYSICS
01	MEASURING; TESTING
N	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1	Sampling; Preparing specimens for investigation
28	Preparing specimens for investigation ; including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
30	Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis