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1. (WO2015050444) PROBE, SYSTEM, AND METHOD FOR NON-INVASIVE MEASUREMENT OF BLOOD ANALYTES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2015/050444 International Application No.: PCT/NL2014/050677
Publication Date: 09.04.2015 International Filing Date: 01.10.2014
IPC:
A61B 5/00 (2006.01) ,A61B 5/145 (2006.01) ,A61B 5/1455 (2006.01) ,G01N 21/65 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1455
using optical sensors, e.g. spectral photometrical oximeters
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21
Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible, or ultra-violet light
62
Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63
optically excited
65
Raman scattering
Applicants:
NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO [NL/NL]; Anna van Buerenplein 1 NL-2595 DA 's-Gravenhage, NL
Inventors:
PEREZ CALERO, Daniel; NL
DAY, James Peter Robert; NL
VOGELS, Jacobus Thomas Wilhelmus Elisabeth; NL
SCHOLTES-TIMMERMAN, Maarten J.; NL
VAN VEEN, Jacobus Johannes Frederik; NL
Agent:
JANSEN, C.M.; NL
Priority Data:
13187155.002.10.2013EP
Title (EN) PROBE, SYSTEM, AND METHOD FOR NON-INVASIVE MEASUREMENT OF BLOOD ANALYTES
(FR) SONDE, SYSTÈME ET PROCÉDÉ POUR LA MESURE NON INVASIVE D'ANALYTES SANGUINS
Abstract:
(EN) The present disclosure concerns a measuring probe (10) for non- invasive in vivo measurement of blood analytes (33) by Raman spectroscopy. The measuring probe (10) comprises a housing (20) having a skin engaging surface (21). The housing (20) comprises a first optical system (1, 3, 4) arranged for providing source light (11) to the skin engaging surface (21) for penetrating a subject's skin (31) by said source light (11) for interacting with the blood analytes (33). The housing (20) further comprises a second optical system (5, 6, 2) arranged for capturing scattered Raman light (12) from the blood analytes (33) for measurement of the blood analytes (33). The first optical system (1, 3, 4) is arranged for providing the source light (11) as a collimated beam (1c) onto the skin (31).
(FR) La présente invention concerne une sonde de mesure (10) pour la mesure non invasive in vivo d'analytes sanguins (33) par spectroscopie Raman. La sonde de mesure (10) comprend un logement (20) présentant une surface (21) qui s'applique sur la peau. Le logement (20) comprend un premier système optique (1, 3, 4) agencé pour fournir de la lumière (11) venant d'une source à la surface (21) qui s'applique sur la peau pour que ladite lumière (11) venant de la source pénètre dans la peau (31) d'un sujet en vue d'interagir avec les analytes sanguins (33). Le logement (20) comprend en outre un deuxième système optique (5, 6, 2) agencé pour capturer la lumière Raman dispersée (12) à partir des analytes sanguins (33) pour la mesure des analytes sanguins (33). Le premier système optique (1, 3, 4) est agencé pour fournir la lumière (11) venant de la source sous forme d'un faisceau collimaté (1c) sur la peau (31).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20160235345EP3052010
Licensing availability request The applicant has requested the International Bureau to indicate the availability for licensing purposes of the invention(s) claimed in this international application