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1. (WO2015048570) EBI2 MODULATORS

Pub. No.:    WO/2015/048570    International Application No.:    PCT/US2014/057897
Publication Date: Fri Apr 03 01:59:59 CEST 2015 International Filing Date: Sat Sep 27 01:59:59 CEST 2014
IPC: A61K 31/4545
Applicants: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
Inventors: PINKERTON, Anthony, B.
ARDECKY, Robert
SERGUIENKO, Eduard, A.
GONZALEZ-LOPEZ, Marcos
GANJI, Santhi, Reddy
ZOU, Jiwen
Title: EBI2 MODULATORS
Abstract:
Provided herein are small molecule Epstein-Barr virus-induced G-protein coupled receptor 2 (EBI2) modulator compounds, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds. EBI2 is a therapeutic target for the treatment of a variety of diseases or conditions. In some embodiments, EBI2 is a therapeutic target for the treatment of diseases or conditions such as, but not limited to, autoimmune diseases or conditions, cancer, and cardiovascular disease.