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1. (WO2015048484) BINDING MOIETIES FOR BIOFILM REMEDIATION

Pub. No.:    WO/2015/048484    International Application No.:    PCT/US2014/057771
Publication Date: Fri Apr 03 01:59:59 CEST 2015 International Filing Date: Sat Sep 27 01:59:59 CEST 2014
IPC: A61K 39/395
A61K 39/40
A61K 39/00
A61K 39/38
A61K 39/02
A61K 39/108
Applicants: TRELLIS BIOSCIENCE, LLC
Inventors: KAUVAR, Lawrence M.
RYSER, Stefan
ESTELLES, Angeles
SIMON, Reyna J.
Title: BINDING MOIETIES FOR BIOFILM REMEDIATION
Abstract:
Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies secreted by human B lymphocytes. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.