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1. (WO2015047220) COMPOSITIONS AND METHODS FOR SINGLE G-LEVEL HLA TYPING
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/047220 International Application No.: PCT/US2013/061377
Publication Date: 02.04.2015 International Filing Date: 24.09.2013
IPC:
C12Q 1/68 (2006.01) ,C07H 21/04 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04
with deoxyribosyl as saccharide radical
Applicants:
GEORGETOWN UNIVERSITY [US/US]; 37th And O Streets, NW Washington, DC 20057-1408, US
Inventors:
NG, Jennifer; US
HURLEY, Carolyn, Katovich; US
TU, Bin; US
MASABERG, Carly; US
Agent:
STEELE, Alan, W.; Foley Hoag LLP Patent Group Seaport West, 155 Seaport Boulevard Boston, MA 02210-2600, US
Priority Data:
Title (EN) COMPOSITIONS AND METHODS FOR SINGLE G-LEVEL HLA TYPING
(FR) COMPOSITIONS ET PROCÉDÉS DE TYPAGE DE HLA DE NIVEAU G UNIQUE
Abstract:
(EN) Provided are methods, kits, and systems useful in the performance of analysis and reporting of highly polymorphic loci, including, in particular, the performance of analysis and reporting of HLA typing. Combining one-step sequencing and sequence-specific oligonucleotide probe hybridization, the methods, kits, and systems offer improved efficiency of HLA typing while providing detailed sequencing information. In certain embodiments the methods and systems comprise one or more software applications to facilitate data acquisition, processing, and reporting.
(FR) L'invention concerne des procédés, des kits et des systèmes utiles pour effectuer des analyses et communiquer les résultats concernant des loci hautement polymorphes, y compris, en particulier, pour effectuer des analyses et communiquer les résultats concernant le typage HLA. Grâce à la combinaison du séquençage en une seule étape et de l'hybridation de sondes oligonucléotidiques spécifiques de séquences, les procédés, kits et systèmes selon l'invention offrent une efficacité améliorée pour le typage HLA, tout en fournissant des informations de séquençage détaillées. Dans certains modes de réalisation, les procédés et systèmes comprennent une ou plusieurs applications logicielles afin de faciliter l'acquisition, le traitement et la communication des données.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)