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1. (WO2015046404) THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR PULMONARY HYPERTENSION

Pub. No.:    WO/2015/046404    International Application No.:    PCT/JP2014/075570
Publication Date: Fri Apr 03 01:59:59 CEST 2015 International Filing Date: Sat Sep 27 01:59:59 CEST 2014
IPC: A61K 31/445
A61K 31/453
A61K 31/454
A61K 45/00
A61P 9/12
A61P 11/00
A61P 43/00
Applicants: TORAY INDUSTRIES, INC.
東レ株式会社
Inventors: NISHIMURA, Yutaka
西村 裕
KATO, Yuko
加藤 祐子
HAYASHI, Shinnosuke
林 新之助
YAMAZAKI, Aiko
山崎 亜衣子
YAMAMOTO, Masashi
山本 将史
ASAOKA, Yoshiji
浅岡 由次
YAMADA, Masateru
山田 将輝
YAMADA Naohiro
山田 尚弘
Title: THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR PULMONARY HYPERTENSION
Abstract:
 The purpose of the present invention is to provide a therapeutic agent or prophylactic agent for pulmonary hypertension to treat pulmonary hypertension on the basis of a dual mechanism of action consisting of a pulmonary vasodilating action and an sEH inhibiting action, and to provide a therapeutic agent or prophylactic agent for pulmonary hypertension to be used in conjunction with a pulmonary vasodilator. The present invention provides a therapeutic agent or prophylactic agent for pulmonary hypertension containing, as active ingredients, a nipecotic acid derivative shown by the formula or a pharmaceutically acceptable salt thereof, and a pulmonary vasodilator.