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1. (WO2015046388) DRUG FOR PREVENTING, TREATING OR PREVENTING METASTASIS OF GIANT CELL TUMOR THAT OCCURS IN BONE OR SOFT PARTS, CHONDROSARCOMA, OR OSTEOSARCOMA, LOCAL INJECTION FOR ARTERIAL EMBOLIZATION, AND ARTIFICIAL BONE

Pub. No.:    WO/2015/046388    International Application No.:    PCT/JP2014/075542
Publication Date: Fri Apr 03 01:59:59 CEST 2015 International Filing Date: Fri Sep 26 01:59:59 CEST 2014
IPC: A61K 45/00
A61K 31/167
A61K 31/196
A61K 31/38
A61K 31/405
A61K 31/427
A61K 31/663
A61K 39/395
A61L 27/00
A61L 31/00
A61P 19/00
A61P 35/00
G01N 33/15
G01N 33/50
G01N 33/68
G01N 33/92
Applicants: NIPPON CHEMIPHAR CO., LTD.
日本ケミファ株式会社
Inventors: TAKEUCHI, Akihiko
武内 章彦
TSUCHIYA, Hiroyuki
土屋 弘行
Title: DRUG FOR PREVENTING, TREATING OR PREVENTING METASTASIS OF GIANT CELL TUMOR THAT OCCURS IN BONE OR SOFT PARTS, CHONDROSARCOMA, OR OSTEOSARCOMA, LOCAL INJECTION FOR ARTERIAL EMBOLIZATION, AND ARTIFICIAL BONE
Abstract:
The present invention provides: a drug for preventing, treating or preventing metastasis of giant cell tumors that occur in the bone or soft parts, chondrosarcoma or osteosarcoma, the drug comprising a PPAR γ agonist and/or a substance having a PPAR γ expression induction activity as an active ingredient; a local injection for arterial embolization; and an artificial bone. The preventing agent, treating agent or metastasis preventing agent, and local injection for arterial embolization or artificial bone are basic treating agents or treating material which are capable of eliminating tumors by inducing apoptosis in the giant cell tumors that occur in the bone or soft parts, chondrosarcoma or osteosarcoma and of eliminating the tumors by inducing the same to differentiate into adipocytes.