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1. (WO2015043614) METHODS AND COMPOSITIONS FOR PREDICTION OF THERAPEUTIC EFFICACY OF CANCER TREATMENTS AND CANCER PROGNOSIS

Pub. No.:    WO/2015/043614    International Application No.:    PCT/EP2013/002899
Publication Date: Fri Apr 03 01:59:59 CEST 2015 International Filing Date: Fri Sep 27 01:59:59 CEST 2013
IPC: G01N 33/569
G01N 33/574
Applicants: BIONTECH AG
STRATIFYER MOLECULAR PATHOLOGY GMBH
Inventors: WIRTZ, Ralph
Title: METHODS AND COMPOSITIONS FOR PREDICTION OF THERAPEUTIC EFFICACY OF CANCER TREATMENTS AND CANCER PROGNOSIS
Abstract:
The invention generally relates to methods and compositions for the prediction of therapeutic efficacy of cancer treatments and the prognosis of cancer. The invention discloses markers that are associated with favorable and unfavorable outcomes, respectively, in certain cancer treatments and are useful as prognostic markers for cancer. Methods involving these markers are disclosed for predicting cancer therapy benefit and prognosing clinical outcome for cancer patients.