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1. (WO2015042852) METHOD FOR DETECTING PULSE-ACTIVATING INJECTION INTERMEDIATES

Pub. No.:    WO/2015/042852    International Application No.:    PCT/CN2013/084415
Publication Date: Fri Apr 03 01:59:59 CEST 2015 International Filing Date: Sat Sep 28 01:59:59 CEST 2013
IPC: A61K 36/57
A61P 9/00
G01N 30/88
G01N 30/02
G01N 5/04
A61K 9/08
A61K 36/258
A61K 36/8968
Applicants: SICHUAN CHUANDA WEST CHINA PHARMACEUTIAL CO., LTD
四川川大华西药业股份有限公司
Inventors: LIU, Ya
刘娅
YAO, Zhe
姚喆
MAO, Jie
毛洁
ZHAN, Xiangjing
詹祥静
GAO, Ning
郜宁
Title: METHOD FOR DETECTING PULSE-ACTIVATING INJECTION INTERMEDIATES
Abstract:
A method for detecting pulse-activating injection intermediates. The pulse-activating injection intermediates comprise red ginseng alcohol extraction liquid, red ginseng water precipitation liquid, radix ophiopogonis first alcohol precipitation liquid, radix ophiopogonis second alcohol precipitation liquid, radix ophiopogonis water precipitation refined liquid through activated carbon, fructus schizandrae first alcohol precipitation liquid, fructus schizandrae second alcohol precipitation liquid, fructus schizandrae water precipitation liquid, fructus schizandrae water precipitation refined liquid through activated carbon, fructus schizandrae distillate and pulse-activating water precipitation filtrate. The detection method comprises detecting ginsenoside content, total solid content and schizandrin content and using HPLC to determine fingerprints of the ginsenoside and the schizandrin. The method can eliminate a technical problem encountered in production timely in an early phase, ensuring quality of the injection.