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1. (WO2015040169) QUINAZOLINE DERIVATIVES AND THEIR USE AS DNA METHYLTRANSFERASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/040169    International Application No.:    PCT/EP2014/070011
Publication Date: 26.03.2015 International Filing Date: 19.09.2014
IPC:
C07D 401/14 (2006.01), C07D 401/12 (2006.01), A61K 31/517 (2006.01), A61P 35/00 (2006.01)
Applicants: PIERRE FABRE MEDICAMENT [FR/FR]; 45, place Abel Gance F-92100 Boulogne-billancourt (FR).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR/FR]; 3, rue Michel Ange F-75016 Paris (FR)
Inventors: HALBY, Ludovic; (FR).
ARIMONDO, Paola Barbara; (FR)
Agent: REGIMBEAU; 20, rue de Chazelles F-75847 Paris Cedex 17 (FR)
Priority Data:
13306281.0 19.09.2013 EP
Title (EN) QUINAZOLINE DERIVATIVES AND THEIR USE AS DNA METHYLTRANSFERASE INHIBITORS
(FR) DÉRIVÉS DE QUINAZOLINE ET LEUR UTILISATION EN TANT QU'INHIBITEURS DE L'ADN MÉTHYLTRANSFÉRASE
Abstract: front page image
(EN)The present invention relates to compounds of the following formula (I): and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds.
(FR)La présente invention concerne des composés de formule (I) ainsi que des des solvates et des sels pharmaceutiquement acceptables de ceux-ci, leurs procédés de préparation, leur utilisation en tant que médicament, notamment dans le traitement du cancer, et des compositions pharmaceutiques contenant de tels composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)