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1. (WO2015039053) HIGHLY EFFICIENT SYNTHESIS OF LONG RNA USING REVERSE DIRECTION APPROACH
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/039053    International Application No.:    PCT/US2014/055711
Publication Date: 19.03.2015 International Filing Date: 15.09.2014
IPC:
C07H 21/02 (2006.01)
Applicants: CHEMGENES CORPORATION [US/US]; 33 Industrial Way Wilmington, MA 01887 (US)
Inventors: SRIVASTAVA, Suresh, C.; (US).
SRIVASTAVA, Naveen, P.; (US)
Agent: HO, David, K.; (US)
Priority Data:
61/877,980 14.09.2013 US
Title (EN) HIGHLY EFFICIENT SYNTHESIS OF LONG RNA USING REVERSE DIRECTION APPROACH
(FR) SYNTHÈSE HAUTEMENT EFFICACE D'ARN LONG PAR UNE APPROCHE DE DIRECTION INVERSE
Abstract: front page image
(EN)The present invention relates to novel process of reverse 5 '→ 3 ' directed synthesis of RNA oligomers in the range of about 100-mer to about 200-mer has been developed and disclosed. Using that method demonstrated high quality RNA synthesis with coupling efficiency approaching 99%.
(FR)L'invention concerne un nouveau procédé de synthèse d'oligomères d'ARN à direction inverse 5'→ 3' dans la plage d'environ 100-mères à environ 200-mères. L'application de ce procédé a permis de faire une synthèse d'ARN de haute qualité avec une efficacité de couplage proche de 99 %.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)