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1. (WO2015038938) MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/038938    International Application No.:    PCT/US2014/055457
Publication Date: 19.03.2015 International Filing Date: 12.09.2014
IPC:
A61K 47/48 (2006.01), A61K 47/30 (2006.01), A61K 38/16 (2006.01), A61P 25/00 (2006.01), A61P 29/00 (2006.01)
Applicants: THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH [US/US]; 11119 North Torrey Pines Road Suite 100 La Jolla, CA 92037 (US).
THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10550 North Torrey Pines Road La Jolla, CA 92037 (US)
Inventors: SHEN, Weijun; (US).
SCHULTZ, Peter, G.; (US).
MUPPIDI, Avinash; (US).
CRAMERI, Andreas; (CH).
AHMAD, Insha; (US).
YANG, Pengyu; (US)
Agent: HARDT, Ingo, H.; (US)
Priority Data:
61/917,816 18.12.2013 US
61/877,799 13.09.2013 US
Title (EN) MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
(FR) AGENTS THÉRAPEUTIQUES MODIFIÉS ET COMPOSITIONS DE CEUX-CI
Abstract: front page image
(EN)Methods and compositions are provided for extending the half-life of a therapeutic agent. One or more half-life extending moieties may be attached to a therapeutic agent, thereby extending the half life of the therapeutic agent. The modified therapeutic agents (mTAs) comprising one or more half-life extending moieties attached to a therapeutic agent may be used to treat a disease or condition in a subject in need thereof.
(FR)L'invention concerne des procédés et des compositions pour prolonger la demi-vie d'un agent thérapeutique. Une ou plusieurs parties prolongeant la demi-vie peuvent être attachées à un agent thérapeutique, prolongeant de cette façon la demi-vie de l'agent thérapeutique. Les agents thérapeutiques modifiés (mTA) comprenant une ou plusieurs parties prolongeant la demi-vie attachées à un agent thérapeutique peuvent être utilisés pour traiter une maladie ou une pathologie chez un sujet qui en a besoin.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)