WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2015038639) THERAPEUTIC ASPARAGINASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/038639    International Application No.:    PCT/US2014/054977
Publication Date: 19.03.2015 International Filing Date: 10.09.2014
IPC:
C12N 9/82 (2006.01), C12N 15/53 (2006.01), A61K 47/48 (2006.01), A61K 38/50 (2006.01), A61P 35/00 (2006.01)
Applicants: SANDIA CORPORATION [US/US]; P.O. Box 5800, MS-0161 Albuquerque, NM 87185 (US).
UNIVERSITY OF MARYLAND [US/US]; Office Of Technology Commercialization 2130 Mitchell Bldg. College Park, MD 20742 (US).
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 West 7th St. Austin, TX 78701 (US)
Inventors: REMPE, Susan; (US).
ROGERS, David, M.; (US).
ANISHKIN, Andriy; (US).
SUKHAREV, Sergei; (US).
LORENZI, Philip, L.; (US).
CHAN, Wai, Kin; (US).
WEINSTEIN, John; (US)
Agent: JOYNER, Amanda, S.; (US)
Priority Data:
61/876,106 10.09.2013 US
Title (EN) THERAPEUTIC ASPARAGINASES
(FR) ASPARAGINASES THÉRAPEUTIQUES
Abstract: front page image
(EN)Provided herein are mutant asparaginase enzymes that lack glutaminase activity. Also provided are methods of treating ASNS-negative cancer cells with a glutaminase-free asparaginase.
(FR)L'invention concerne des enzymes asparaginases mutantes qui ne présentent pas l'activité de la glutaminase. L'invention concerne également des méthodes de traitement de cellules cancéreuses négatives à teneur en ASNS avec une asparaginase exempte de glutaminase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)