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Machine translation
1. (WO2015038625) ADENO-ASSOCIATED VIRUS FACTOR VIII VECTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/038625    International Application No.:    PCT/US2014/054960
Publication Date: 19.03.2015 International Filing Date: 10.09.2014
IPC:
C07K 14/755 (2006.01), A61K 48/00 (2006.01), C12N 15/86 (2006.01)
Applicants: BIOMARIN PHARMACEUTICAL INC. [US/US]; 105 Digital Drive Novato, CA 94949 (US).
UNIVERSITY COLLEGE LONDON [GB/GB]; Gower Street London WC1E 6BT (GB)
Inventors: COLOSI, Peter, Cameron; (US).
NATHWANI, Amit; (GB).
MCINTOSH, Jenny; (GB).
TUDDENHAM, Edward; (GB)
Agent: SINTICH, Sharon, M.; (US)
Priority Data:
61/877,042 12.09.2013 US
Title (EN) ADENO-ASSOCIATED VIRUS FACTOR VIII VECTORS
(FR) VECTEURS DU FACTEUR VIII DE VIRUS ASSOCIÉ AUX ADÉNOVIRUS
Abstract: front page image
(EN)The invention provides improved adeno-associated virus (AAV) Factor VIII (FVIII) vectors, including AAV FVIII vectors that produce a functional Factor VIII polypeptide and AAV FVIII vectors with high expression activity.
(FR)L'invention concerne des vecteurs améliorés du facteur VIII (FVIII) de virus associé aux adénovirus (AAV), y compris des vecteurs du FVIII d'AAV qui produisent un polypeptide de facteur VIII fonctionnel et des vecteurs de FVIII d'AAV possédant une forte activité d'expression.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)