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1. (WO2015038493) SYNTHESIS OF NOVEL ASYMMETRIC BOW-TIE PAMAM DENDRIMER-BASED CONJUGATES FOR TUMOR-TARGETING DRUG DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/038493    International Application No.:    PCT/US2014/054655
Publication Date: 19.03.2015 International Filing Date: 09.09.2014
IPC:
C07D 305/14 (2006.01), C07D 409/04 (2006.01), C07D 325/00 (2006.01), A61K 31/337 (2006.01), A61P 35/00 (2006.01)
Applicants: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK [US/US]; 35 State Street Albany, New York 12207 (US)
Inventors: OJIMA, Iwao; (US).
WANG, Tao; (CN).
TENG, Yu-Han; (TW)
Agent: GROLZ, Edward W.; (US)
Priority Data:
61/875,943 10.09.2013 US
62/035,794 11.08.2014 US
Title (EN) SYNTHESIS OF NOVEL ASYMMETRIC BOW-TIE PAMAM DENDRIMER-BASED CONJUGATES FOR TUMOR-TARGETING DRUG DELIVERY
(FR) SYNTHÈSE DE NOUVEAUX CONJUGUÉS ASYMÉTRIQUES À BASE D'UN DENDRIMÈRE PAMAM EN NŒUD PAPILLON POUR ADMINISTRATION DE MÉDICAMENTS CIBLÉE VERS UNE TUMEUR
Abstract: front page image
(EN)The present disclosure relates to a dendrimer-based conjugate of the formula Vm-D-C-D'-(T-F)n, which is useful for tumor targeting drug delivery. The use of asymmetric dendrimers allow for specific targeting as well as synthetic reproducibility.
(FR)La présente invention concerne un conjugué à base d'un dendrimère de formule Vm-D-C-D'-(T-F)n qui est utile pour l'administration de médicaments ciblée vers une tumeur. L'utilisation de dendrimères asymétriques permet un ciblage spécifique ainsi qu'une reproductibilité de synthèse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)