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1. (WO2015036792) THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/036792    International Application No.:    PCT/GB2014/052787
Publication Date: 19.03.2015 International Filing Date: 12.09.2014
IPC:
A61K 47/12 (2006.01), A61K 9/51 (2006.01), A61K 31/00 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; SE-151 85 Södertälje (SE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 2 Kingdom Street London Greater London W2 6BD (GB) (MG only)
Inventors: ASHFORD, Marianne Bernice; (GB).
NOLAN,James, Martin, III; (US).
SHIN, Eyoung; (US).
SONG, Young-Ho; (US).
TROIANO, Greg; (US).
WANG, Hong; (US)
Agent: ASTRAZENECA INTELLECTUAL PROPERTY; AstraZeneca Mereside Alderley Park Macclesfield Cheshire SK10 4TG (GB)
Priority Data:
61/878,227 16.09.2013 US
61/939,332 13.02.2014 US
Title (EN) THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME
(FR) NANOPARTICULES POLYMÈRES THÉRAPEUTIQUES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
Abstract: front page image
(EN)Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol- -yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
(FR)L'invention concerne des nanoparticules polymères qui comprennent un agent thérapeutique qui est 2-(3-((7-(3-(éthyl(2-hydroxyéthyl)amino)propoxy)quinazoline-4-yl)amino)-1H-pyrazole- -yl)-N-(3-fluorophényl)acétamide (également appelé AZD1152 hqpa) ou un sel de qualité pharmaceutique de celui-ci, ainsi que des procédés de fabrication et d'utilisation de telles nanoparticules thérapeutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)