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Machine translation
1. (WO2015035239) REAGENTS AND METHODS FOR SCREENING MPS I, II, IIIA, IIIB, IVA, VI, AND VII
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/035239    International Application No.:    PCT/US2014/054398
Publication Date: 12.03.2015 International Filing Date: 05.09.2014
IPC:
A61K 38/47 (2006.01)
Applicants: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION [US/US]; 4311 11th Avenue Northeast, Suite 500 Seattle, WA 98105-4608 (US)
Inventors: BARCENAS RODRIGUEZ, Mariana, Natali; (US).
TURECEK, Frantisek; (US).
SCOTT, C., Ronald; (US).
GELB, Michael, H.; (US).
KUMAR, Arun, Babu; (US).
HOCUTT, Frances; (US).
SPACIL, Zdenek; (US)
Agent: RENZONI, George, E.; (US)
Priority Data:
61/960,113 09.09.2013 US
61/968,021 20.03.2014 US
61/874,331 05.09.2013 US
61/960,102 09.09.2013 US
61/949,970 07.03.2014 US
61/874,293 05.09.2013 US
62/012,020 13.06.2014 US
Title (EN) REAGENTS AND METHODS FOR SCREENING MPS I, II, IIIA, IIIB, IVA, VI, AND VII
(FR) RÉACTIFS ET PROCÉDÉS DE CRIBLAGE MPS I, II, IIIA, IIIB, IVA, VI, ET VII
Abstract: front page image
(EN)Reagents, methods, and kits for assaying enzymes associated with lysosomal storage diseases MPS-I, MPS-II, MPS-IIIA, MPS-IIIB, MPS-IV A, MPS-VI, and MPS VII. In one aspect, the invention provides methods for assaying one or more enzymes associated with a lysosomal storage disease. In a first embodiment, the method includes: (a) contacting a sample with a first solution to provide a solution comprising one or more lysosomal enzymes; (b) contacting the one or more lysosomal enzymes in solution with an enzyme substrate for each lysosomal enzyme to be analyzed and incubating the substrates with the enzymes for a time sufficient to provide a solution comprising an enzyme product for each lysosomal enzyme present in the sample.
(FR)L'invention concerne des réactifs, des procédés et des kits de dosage d'enzymes associés à des maladies lysosomales MPS-I, MPS-II, MPS-IIIA, MPS-IIIB, MPS-IVA, MPS-VI et MPS-VII.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)