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1. (WO2015032272) C-ARYL GLUCOSIDE DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/032272 International Application No.: PCT/CN2014/084717
Publication Date: 12.03.2015 International Filing Date: 19.08.2014
IPC:
C07H 9/04 (2006.01) ,C07D 409/14 (2006.01) ,C07D 409/10 (2006.01) ,A61P 3/10 (2006.01) ,A61P 9/10 (2006.01) ,A61P 27/02 (2006.01) ,A61P 25/00 (2006.01) ,A61P 13/12 (2006.01) ,A61P 5/50 (2006.01) ,A61P 3/06 (2006.01) ,A61P 3/04 (2006.01) ,A61P 3/00 (2006.01) ,A61P 9/12 (2006.01)
Applicants: JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD.[CN/CN]; The 10th Industrial Sub-Zone of Development Zone Lianyungang, Jiangsu 222047, CN
Inventors: ZHONG, Huijuan; CN
LIAO, Jianchun; CN
YU, Hongping; CN
XU, Yaochang; CN
LI, Qing; CN
CHEN, Jianghua; CN
GAO, Peng; CN
TAN, Songliang; CN
WANG, Shaobao; CN
Agent: GE CHENG & CO., LTD.; Level 19, Tower E3, The Towers, Oriental Plaza No.1, East Chang An Avenue, Dongcheng District Beijing 100738, CN
Priority Data:
201310408357.909.09.2013CN
Title (EN) C-ARYL GLUCOSIDE DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF
(FR) DÉRIVÉ DE GLUCOSIDE DE TYPE C-ARYLE, SON PROCÉDÉ DE PRÉPARATION, ET SES APPLICATIONS MÉDICALES
(ZH) C-芳基葡糖苷衍生物、其制备方法及其在医药上的应用
Abstract: front page image
(EN) The present invention relates to a C-aryl glucoside derivative, a preparation method for same, and medical applications thereof. Specifically, the present invention relates to compounds as represented by formula I, and, tautomers, enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts of the compounds, a preparation method for same or a pharmaceutical composition comprising the compounds, and applications thereof as a therapeutic agent and particularly as a sodium-dependent glucose transporter protein (SGLT) inhibitor.
(FR) Cette invention concerne un dérivé de glucoside de type C-aryle, son procédé de préparation, et ses applications médicales. Plus spécifiquement, la présente invention concerne des composés représentés par la formule I, et les tautomères, les énantiomères, les diastéréomères, les racémates et les sels pharmaceutiquement acceptables desdits composés, leur procédé de préparation ou une composition pharmaceutique les contenant, et leurs applications à titre d'agents thérapeutiques et en particulier à titre d'inhibiteurs de la protéine transporteur de glucose sodium-dépendante (SGLT).
(ZH) 本发明涉及C-芳基葡糖苷衍生物、其制备方法及其在医药上的应用。具体而言,本发明涉及如通式I所示的化合物以及它们的互变异构体、对映体、非对映体、消旋体和可药用的盐,其制备方法或含有该化合物的药物组合物,以及作为治疗剂特别是作为钠依赖性葡糖转运蛋白(SGLT)抑制剂的用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)