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1. (WO2015031604) GENE EXPRESSION SIGNATURES PREDICTIVE OF SUBJECT RESPONSE TO A MULTI-KINASE INHIBITOR AND METHODS OF USING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/031604    International Application No.:    PCT/US2014/053142
Publication Date: 05.03.2015 International Filing Date: 28.08.2014
IPC:
G01N 33/48 (2006.01)
Applicants: CROWN BIOSCIENCE, INC. (TAICANG) [CN/CN]; 6 Beijing West Road Taicang Economic Development Area Jiangsu Province (CN)
Inventors: GUO, Sheng; (CN).
CHEN, Dawei; (CN).
ZHANG, Juan; (CN).
CAI, Jie; (CA).
LI, Henry Qixiang; (US)
Agent: WU, Nan; (US)
Priority Data:
PCT/CN2013/082487 28.08.2013 CN
Title (EN) GENE EXPRESSION SIGNATURES PREDICTIVE OF SUBJECT RESPONSE TO A MULTI-KINASE INHIBITOR AND METHODS OF USING THE SAME
(FR) SIGNATURES D'EXPRESSION GÉNIQUE PERMETTANT DE PRÉDIRE LA RÉPONSE D'UN SUJET À UN INHIBITEUR MULTIKINASE ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Gene expression signature predictive of cancer patient response to multi-kinase inhibitor is disclosed. Also disclosed are methods predicting the efficacy of the multi-kinase inhibitor for treating cancer in a patient. Also disclosed are methods for distinguishing responders from non-responders to a multi-kinase inhibitor in treating cancer. Also disclosed are methods for treating a cancer patient with a multi-kinase inhibitor.
(FR)La présente invention concerne une signature d'expression génique permettant de prédire la réponse d'un patient cancéreux à un inhibiteur multikinase. L'invention concerne également des procédés permettant de prédire l'efficacité d'un inhibiteur multikinase en matière de traitement du cancer chez un patient. L'invention concerne aussi des procédés permettant de distinguer les patients répondeurs des patients non répondeurs à un inhibiteur multikinase dans le cadre du traitement du cancer. L'invention concerne encore des méthodes de traitement d'un patient cancéreux faisant appel à un inhibiteur multikinase.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)