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Machine translation
1. (WO2015028550) BINDING POLYPEPTIDES HAVING A MUTATED SCAFFOLD
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/028550    International Application No.:    PCT/EP2014/068259
Publication Date: 05.03.2015 International Filing Date: 28.08.2014
IPC:
C07K 14/31 (2006.01)
Applicants: AFFIBODY AB [SE/SE]; Gunnar Asplunds Allé 24 SE-171 69 Solna (SE)
Inventors: NORDLING, Erik; (SE).
NILSSON, Joakim; (SE).
STRÖMBERG, Patrik; (SE)
Agent: AWAPATENT AB; Niklas Mattsson Box 45086 S-104 30 Stockholm (SE)
Priority Data:
13182022.7 28.08.2013 EP
Title (EN) BINDING POLYPEPTIDES HAVING A MUTATED SCAFFOLD
(FR) POLYPEPTIDES SE LIANT À C5
Abstract: front page image
(EN)The present disclosure relates to a class of engineered polypeptides and provides a polypeptide comprising the sequence EX2X3X4AX6X7EIX10 X11 LPNLX16X17X18QX20 X21AFIX25X26LX28X29X30 PX32QSX35X36LLX39E AKKX45X46X47Q. The present disclosure also relates to populations of polypeptide variants based on a common scaffold, each polypeptide in the population comprising the amino acid sequence EX2X3X4AX6X7EIX10 X11 LPNLX16X17X18QX20 X21AFIX25X26LX28X29X30 PX32QSX35X36LLX39E AKKLX45X46X47Q, and methods for selecting a desired polypeptide having an affinity for a predetermined target from said population.
(FR)La présente divulgation concerne une classe de polypeptides techniques et concerne un polypeptide comprenant la séquence EX2X3X4AX6X7EIX10 X11 LPNLX16X17X18QX20 X21AFIX25X26LX28X29X30 PX32QSX35X36LLX39E AKKX45X46X47Q. La présente divulgation concerne également des populations de variants polypeptidiques basés sur un échafaudage commun, chaque polypeptide dans la population comprenant la séquence d'acides aminés EX2X3X4AX6X7EIX10 X11 LPNLX16X17X18QX20 X21AFIX25X26LX28X29X30 PX32QSX35X36LLX39E AKKLX45X46X47Q, ainsi que des procédés pour sélectionner un polypeptide souhaité ayant une affinité pour une cible prédéfinie au sein de ladite population.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)