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1. (WO2015004038) ANTIBODIES TO β2-GLYCOPROTEIN I AND THERAPEUTIC USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/004038 International Application No.: PCT/EP2014/064400
Publication Date: 15.01.2015 International Filing Date: 07.07.2014
IPC:
C07K 16/18 (2006.01) ,A61K 39/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
ONCONOX APS [DK/DK]; Ole Maaløes Vej 3 DK-2200 Copenhagen, DK
Inventors:
TEDESCO, Francesco; IT
MERONI, Pier Luigi; IT
SBLATTERO, Daniele; IT
Agent:
BANFI, Paolo; IT
Priority Data:
61/844,50510.07.2013US
Title (EN) ANTIBODIES TO β2-GLYCOPROTEIN I AND THERAPEUTIC USES THEREOF
(FR) ANTICORPS DIRIGÉS CONTRE LA Β2-GLYCOPROTÉINE I ET USAGES THÉRAPEUTIQUES DE CEUX-CI
Abstract:
(EN) Human recombinant antibodies or fragments thereof having specificity for the β2-glycoprotein I (β2GΡΙ), pharmaceutical compositions containing same and use thereof in a method for treating or preventing thrombus formation and fetal loss in a patient affected by antiphospholipid syndrome (APS).
(FR) L'invention concerne des anticorps recombinants humains ou des fragments de ceux-ci ayant une spécificité pour la β2-glycoprotéine I (β2GΡI), des compositions pharmaceutiques les contenant et leur utilisation dans un procédé pour traiter ou prévenir une thrombose et une perte fœtale chez un sujet atteint du syndrome des antiphospholipides (SAPL).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)