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1. (WO2014210448) COMPOSITIONS AND METHODS RELATING TO MYOMAKER-INDUCED MUSCLE CELL FUSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/210448    International Application No.:    PCT/US2014/044554
Publication Date: 31.12.2014 International Filing Date: 27.06.2014
IPC:
A61K 45/00 (2006.01), A61K 48/00 (2006.01), C12N 15/09 (2006.01)
Applicants: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 W. 7th Street Austin, TX 78701 (US)
Inventors: OLSON, Eric; (US).
MILLAY, Douglas, P.; (US)
Agent: HIGHLANDER, Steven, L.; (US)
Priority Data:
61/840,211 27.06.2013 US
Title (EN) COMPOSITIONS AND METHODS RELATING TO MYOMAKER-INDUCED MUSCLE CELL FUSION
(FR) COMPOSITIONS ET PROCÉDÉS RELATIFS À LA FUSION DE CELLULES MUSCULAIRES INDUITE PAR MYOMAKER
Abstract: front page image
(EN)The present disclosure describes the fusogenic activity of the Myomaker protein. This polypeptide, when expressed in non-muscle cells, is able to drive fusion of the cell with a muscle cell, but not with other non-muscle cells. The use of this protein and cell expressing it in the delivery of exogenous genetic material to muscle cells also is described.
(FR)La présente invention concerne l'activité fusogène de la protéine Myomaker. Ce polypeptide, lorsqu'il est exprimé dans des cellules non musculaires, est capable de diriger la fusion de la cellule avec une cellule musculaire, mais non avec d'autres cellules non musculaires. L'invention concerne également l'utilisation de cette protéine et son expression dans la délivrance de matériel génétique exogène à des cellules musculaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)