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1. (WO2014210306) THREE-DIMENSIONAL BIO-MEDICAL PROBE SENSING AND CONTACTING STRUCTURES WITH ADDRESSIBLITY AND TUNABILITY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/210306 International Application No.: PCT/US2014/044333
Publication Date: 31.12.2014 International Filing Date: 26.06.2014
IPC:
A61B 5/04 (2006.01) ,A61B 5/05 (2006.01) ,A61B 5/145 (2006.01) ,A61B 5/1473 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
05
Measuring for diagnosis by means of electric currents or magnetic fields
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
145
Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1468
using chemical or electrochemical methods, e.g. by polarographic means
1473
invasive, e.g. introduced into the body by a catheter
Applicants: THE PENN STATE RESEARCH FOUNDATION[US/US]; 304 Old Main University Park, PA 16802, US
Inventors: FONASH, Stephen, J.; US
NAM, Wook, Jun; US
Agent: WATHEN, Douglas, L.; US
Priority Data:
61/839,52326.06.2013US
Title (EN) THREE-DIMENSIONAL BIO-MEDICAL PROBE SENSING AND CONTACTING STRUCTURES WITH ADDRESSIBLITY AND TUNABILITY
(FR) STRUCTURES DE DÉTECTION ET DE CONTACT DE SONDE BIOMÉDICALE TRIDIMENSIONNELLE
Abstract:
(EN) A three dimensional biomedical probe device is provided that includes a planar substrate. A probe structure is supported on the planar substrate. The probe structure has a base and a portion essentially perpendicular to the base extending along a length to a tip and has a linear dimension at the tip of said probe structure of between 5 nanometers (nm) and 5 microns thereby defining an AC, DC, or transient current, charge, or voltage sensing probe. In one variation, this probe is the electrical contact to the biomedical medium. In another variation this probe is the gate electrode of a field effect transistor (FET). An array of selectively electrically addressable such devices is also provided giving the ability to sample the physiological activity at many positions within cells, fluids and intercellular regions without the need for mechanical motion and inducing cellular lysis.
(FR) L'invention concerne un dispositif de sonde biomédicale tridimensionnelle, qui comprend un substrat plat. Une structure de sonde est supportée sur le substrat plat. La structure de sonde comprend une base et une partie essentiellement perpendiculaire à la base s'étendant le long d'une longueur jusqu'à une pointe, et a une dimension linéaire à la pointe de ladite structure de sonde comprise entre 5 nanomètres (nm) et 5 microns, en définissant ainsi une sonde de détection de courant alternatif, de courant continu, de courant transitoire, de charge ou de tension. Dans une première variante, cette sonde est le contact électrique avec le support biomédical. Dans une autre variante, cette sonde est l'électrode de grille d'un transistor à effet de champ (FET). Un réseau de dispositifs sélectivement électriquement adressables fournit également la capacité d'échantillonner l'activité physiologique dans de nombreuses positions dans des cellules, des fluides et des régions intracellulaires, sans nécessiter de mouvement mécanique ni induire de lyse cellulaire.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)