WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2014210167) LABELED PKG-1-ALPHA-BINDING COMPOUNDS AND THEIR USE IN IMAGING AND QUANTIFYING PAIN
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/210167 International Application No.: PCT/US2014/044115
Publication Date: 31.12.2014 International Filing Date: 25.06.2014
IPC:
A61K 31/416 (2006.01) ,A61K 31/40 (2006.01)
Applicants: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK[US/US]; 412 Low Memorial Library 535 West 116th Street New York, NY 10027, US
Inventors: KOREN, Andrei, O.; US
DENG, Shi-Xian; US
LANDRY, Donald, W.; US
DIVGI, Chaitanya; US
Agent: KOLE, Lisa, B.; US
Priority Data:
61/839,64926.06.2013US
Title (EN) LABELED PKG-1-ALPHA-BINDING COMPOUNDS AND THEIR USE IN IMAGING AND QUANTIFYING PAIN
(FR) COMPOSÉS MARQUÉS DE LIAISON À LA PKG-1-ALPHA ET LEUR UTILISATION POUR PRENDRE DES IMAGES ET QUANTIFIER LA DOULEUR
Abstract:
(EN) The present invention relates to the use of compounds that selectively bind to activated protein kinase G1 alpha for imaging the anatomic basis for chronic pain. Such imaging may also be used to objectively quantify chronic pain. Specifically, fluorine-18 and carbon -11 labeled NOP compouds, [18F] NOP46 and [11 C]NOP46, are disclosed for use as imaging agents for detecting and quantifying neuropathic pain.
(FR) L'invention concerne l'utilisation de composés qui se lient de manière sélective à la protéine kinase G1 alpha activée pour prendre des images des structures anatomiques pour la douleur chronique. La prise d'image peut également servir à quantifier objectivement la douleur chronique. L'invention concerne plus précisément des composés NOP marqués au fluor 18 et au carbone 11, à savoir [18F] NOP46 et [11 C]NOP46, utilisés comme agents d'imagerie pour détecter et quantifier la douleur neuropathique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)