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1. (WO2014210142) CORTICAL BONE-DERIVED STEM CELLS

Pub. No.:    WO/2014/210142    International Application No.:    PCT/US2014/044077
Publication Date: Thu Jan 01 00:59:59 CET 2015 International Filing Date: Thu Jun 26 01:59:59 CEST 2014
IPC: C12N 5/0775
Applicants: TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Inventors: HOUSER, Steven, R.
KUBO, Hajime
DURAN, Jason, Mathew
SHARP, Thomas, E.
Title: CORTICAL BONE-DERIVED STEM CELLS
Abstract:
The present invention provides an isolated population of cortical bone- derived stem cells (CBSCs) and cells derived thereof. The CBSCs can survive when injected into the ischemic heart and have the potential to differentiate into cardiac myocytes with mature function and to secrete factors that promote endogenous repair.