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1. (WO2014207401) MODULATORS OF THE NAV1.9 SODIUM CHANNEL FOR THE TREATMENT OF AN INFLAMMATORY SKIN DISEASE AND DIAGNOSTIC METHODS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/207401 International Application No.: PCT/FR2014/051642
Publication Date: 31.12.2014 International Filing Date: 27.06.2014
IPC:
C07K 16/28 (2006.01) ,A61P 17/10 (2006.01) ,A61K 39/395 (2006.01)
Applicants: GALDERMA RESEARCH & DEVELOPMENT[FR/FR]; 2400 Route des Colles Les Templiers F-06410 Biot, FR
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE[FR/FR]; 3 rue Michel Ange F-75016 Paris, FR
UNIVERSITE D'AIX-MARSEILLE[FR/FR]; Jardin du Pharo 58 boulevard Charles Livon F-13007 Marseille, FR
Inventors: CREST, Marcel; FR
DELMAS, Patrick; FR
LONIGRO-RAME, Aurélie; FR
OSORIO, Nancy; FR
Agent: VERHAEGHE BECT, Elodie; FR
Priority Data:
135634928.06.2013FR
Title (EN) MODULATORS OF THE NAV1.9 SODIUM CHANNEL FOR THE TREATMENT OF AN INFLAMMATORY SKIN DISEASE AND DIAGNOSTIC METHODS
(FR) MODULATEURS DU CANAL SODIQUE NAV1.9 POUR LE TRAITEMENT D'UNE MALADIE CUTANÉE INFLAMMATOIRE ET MÉTHODES DIAGNOSTIQUES
Abstract:
(EN) The invention relates to the use of a modulator of the Nav1.9 sodium channel in the treatment or prevention of an inflammatory skin disease. The invention also relates to a pharmaceutical composition including a modulator of the Nav1.9 sodium channel, as well as to in vitro diagnostic methods based on the detection or quantification of Nav1.9.
(FR) L'invention a pour objet l'utilisation d'un modulateur du canal sodique Nav1.9 dans le traitement ou la prévention d'une maladie cutanée inflammatoire. L'invention concerne également une composition pharmaceutique comprenant un modulateur du canal sodique Nav 1.9 ainsi que des méthodes de diagnostic in vitro basées sur la détection ou la quantification de Nav 1.9.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: French (FR)
Filing Language: French (FR)