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1. (WO2014207166) A METHOD OF DETERMINING OR PREDICTING A CHARACTERISTIC OF A CELL
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/207166 International Application No.: PCT/EP2014/063625
Publication Date: 31.12.2014 International Filing Date: 26.06.2014
IPC:
G01N 33/50 (2006.01) ,G05B 17/02 (2006.01) ,G05B 13/04 (2006.01) ,C12M 1/36 (2006.01) ,C12M 1/34 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
05
CONTROLLING; REGULATING
B
CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
17
Systems involving the use of models or simulators of said systems
02
electric
G PHYSICS
05
CONTROLLING; REGULATING
B
CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
13
Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion
02
electric
04
involving the use of models or simulators
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
36
including condition or time responsive control, e.g. automatically controlled fermentors
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
34
Measuring or testing with condition measuring or sensing means, e.g. colony counters
Applicants: VALITACELL LIMITED[IE/IE]; Fort Henry Business Park Co. Tipperary Ballina, IE
Inventors: THOMPSON, Ben; GB
JAMES, David; GB
DAVIES, Sarah Louise; GB
Agent: PURDY, Hugh Barry; IE
Priority Data:
13173871.826.06.2013EP
13185979.525.09.2013EP
Title (EN) A METHOD OF DETERMINING OR PREDICTING A CHARACTERISTIC OF A CELL
(FR) PROCÉDÉ POUR DÉTERMINER OU PRÉDIRE UNE CARACTÉRISTIQUE D'UNE CELLULE
Abstract:
(EN) A method of determining or predicting a characteristic of a query cell, for example the identity of the query cell, is described. The method comprises the steps of incubating the query cell with a plurality of chemical cell stressor molecules, determining the growth response of the query cell in the presence of each of the at least three chemical cell stressor molecules to generate a query cell-specific growth response fingerprint, and comparing the query cell- specific growth response fingerprint with one or more reference cell-specific growth response fingerprints corresponding to one or more cells having known characteristics. The characteristic of the cell (for example the identity of the cell) may be determined based on the level of correlation between the query cell-specific growth response fingerprint and the one or more reference cell-specific growth response fingerprints.
(FR) L'invention concerne un procédé pour déterminer ou prédire une caractéristique d'une cellule de requête, par exemple l'identité de la cellule de requête. Le procédé comprend les étapes consistant à incuber la cellule de requête avec une pluralité de molécules de stresseur de cellule chimiques, déterminer la réponse de croissance de la cellule de requête en présence de chacune des au moins trois molécule de stresseur de cellule chimiques pour générer une empreinte de réponse de croissance spécifique à la cellule de requête, et comparer l'empreinte de réponse de croissance spécifique à la cellule de requête avec une ou plusieurs empreintes de réponse de croissance spécifique à la cellule de référence correspondant à une ou plusieurs cellules ayant des caractéristiques connues. La caractéristique de la cellule (par exemple l'identité de la cellule) peut être déterminée sur la base du niveau de corrélation entre l'empreinte de réponse de croissance spécifique à la cellule de requête et la ou les empreintes de réponse de croissance spécifique à la cellule de référence.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)