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1. (WO2014205447) MICROFLUIDIC SYSTEM WITH FLUID PICKUPS

Pub. No.:    WO/2014/205447    International Application No.:    PCT/US2014/043715
Publication Date: Thu Dec 25 00:59:59 CET 2014 International Filing Date: Tue Jun 24 01:59:59 CEST 2014
IPC: G01N 1/00
Applicants: BIO-RAD LABORATORIES, INC.
MAKAREWICZ, Anthony, J., Jr.
BOUSSE, Luc
SCHIAFFINO, Stefano
Inventors: MAKAREWICZ, Anthony, J., Jr.
BOUSSE, Luc
SCHIAFFINO, Stefano
Title: MICROFLUIDIC SYSTEM WITH FLUID PICKUPS
Abstract:
Microfluidic system, including methods and apparatus, for processing fluid, such as by droplet generation. In some embodiments, the system may include a well and a channel component attached to the well. The channel component may include (a) a body, (b) an input tube (a "fluid pickup") projecting from a bottom surface of the body and having an open bottom end disposed in the input well, (c) a microchannel, and (d) a passage extending through the input tube and the body and connecting the well to the microchannel. The system may be configured to receive a sample- containing fluid in the well and retain the sample-containing fluid below a top end of the passage, until a pressure differential is created that drives at least a portion of the sample-containing fluid from the well via the passage and through the microchannel.