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Machine translation
1. (WO2014205380) COMPOUNDS AND COMPOUNDS FOR USE IN METHODS FOR TREATING DISEASES OR CONDITIONS MEDIATED BY PROTEIN DISULFIDE ISOMERASE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/205380 International Application No.: PCT/US2014/043467
Publication Date: 24.12.2014 International Filing Date: 20.06.2014
IPC:
C07D 211/62 (2006.01) ,A61K 31/445 (2006.01) ,A61P 7/02 (2006.01) ,A61P 35/00 (2006.01) ,A61P 29/00 (2006.01) ,A61P 31/00 (2006.01)
Applicants: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.[US/US]; 330 Brookline Avenue Boston, MA 02215, US
THE BROAD INSTITUTE, INC.[US/US]; 7 Cambridge Center Cambridge, MA 02142, US
Inventors: FLAUMENHAFT, Robert; US
NAG, Partha, Pratim; US
PILYUGINA, Tatiana; US
PU, Jun; US
DANDAPANI, Sivaraman; US
MUNOZ, Benito; US
Agent: DAVIS, Steven, G.; US
Priority Data:
61/837,82021.06.2013US
Title (EN) COMPOUNDS AND COMPOUNDS FOR USE IN METHODS FOR TREATING DISEASES OR CONDITIONS MEDIATED BY PROTEIN DISULFIDE ISOMERASE
(FR) COMPOSÉS ET COMPOSÉS DESTINÉS À ÊTRE UTILISÉS DANS DES MÉTHODES DE TRAITEMENT DE MALADIES OU D'ÉTATS MÉDIÉS PAR LA PROTÉINE DISULFIDE ISOMÉRASE
Abstract: front page image
(EN) The invention provides compounds of formula (I) that inhibit PDI, for use in methods to treat or prevent a disease or condition in a subject that would benefit by inhibition of PDI. Formula (I)
(FR) L'invention concerne des composés représentés par la formule (I) qui inhibe la PDI, destinés à être utilisés pour traiter ou prévenir une maladie ou un état chez un sujet pour qui une inhibition de PDI serait bénéfique. Formule (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)