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1. WO2014203045 - A NOVEL, GREEN AND COST EFFECTIVE PROCESS FOR SYNTHESIS OF TERT-BUTYL (3R,5S)-6-OXO-3,5-DIHYDROXY-3,5-O-ISOPROPYLIDENE-HEXANOATE

Publication Number WO/2014/203045
Publication Date 24.12.2014
International Application No. PCT/IB2013/056805
International Filing Date 22.08.2013
IPC
C07D 319/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
319Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
041,3-Dioxanes; Hydrogenated 1,3-dioxanes
06not condensed with other rings
CPC
C07D 319/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
319Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
041,3-Dioxanes; Hydrogenated 1,3-dioxanes
06not condensed with other rings
Applicants
  • LUPIN LIMITED [IN]/[IN]
Inventors
  • ROY, Bhairabnath
  • SINGH, Girij, Pal
  • LATHI, Piyush, Suresh
  • AGRAWAL, Manoj, Kunjabihari
  • MITRA, Rangan
  • TRIVEDI, Anurag
  • PISE, Vijay, Sadashiv
  • RUPANWAR, Manoj
Agents
  • MAJUMDAR, Subhatosh
Priority Data
2096/MUM/201320.06.2013IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A NOVEL, GREEN AND COST EFFECTIVE PROCESS FOR SYNTHESIS OF TERT-BUTYL (3R,5S)-6-OXO-3,5-DIHYDROXY-3,5-O-ISOPROPYLIDENE-HEXANOATE
(FR) NOUVEAU PROCÉDÉ ÉCOLOGIQUE ET ÉCONOMIQUE POUR LA SYNTHÈSE DE TERT-BUTYL (3R,5S)-6-OXO-3,5-DIHYDROXY-3,5-O-ISOPROPYLIDÈNE-HEXANOATE
Abstract
(EN)
The present invention provides a process of preparation of an intermediate useful for the preparation of statins more particularly the present invention relates to an eco-friendly and cost effective process for the preparation of tert -butyl (3R,5S)-6-oxo-3,5-dihydroxy- 3,5-O-isopropylidene-hexanoate [I].
(FR)
La présente invention concerne un procédé pour la préparation d'un intermédiaire utile pour la préparation de statines plus particulièrement la présente invention concerne un procédé écologique et économique pour la préparation de tert -butyl (3R,5S)-6-oxo-3,5-dihydroxy- 3,5-O-isopropylidène-hexanoate [I].
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