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1. (WO2014202627) WHOLE-CELL SYSTEM FOR CYTOCHROME P450 MONOOXYGENASES BIOCATALYSIS

Pub. No.:    WO/2014/202627    International Application No.:    PCT/EP2014/062749
Publication Date: Thu Dec 25 00:59:59 CET 2014 International Filing Date: Wed Jun 18 01:59:59 CEST 2014
IPC: C12P 33/00
C12P 7/62
C12N 9/06
C12N 9/02
Applicants: SANOFI
Inventors: GERBER, Adrian
HANNEMANN, Frank
BLEIF, Sabrina
KLESER, Michael
BERNHARDT, Rita
Title: WHOLE-CELL SYSTEM FOR CYTOCHROME P450 MONOOXYGENASES BIOCATALYSIS
Abstract:
The subject of the present invention is a whole-cell catalysis process for converting substrates of cytochrome P450 monooxygenases of eukaryotic origin into valuable biotechnological products. The subject of the present invention is also microorganisms genetically engineered to achieve those biotransformations with high rates and processes to prepare these microorganism strains.