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1. (WO2014201972) BENZIMIDAZOLE-2-PIPERAZINE HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD AND USE THEREOF

Pub. No.:    WO/2014/201972    International Application No.:    PCT/CN2014/079827
Publication Date: Thu Dec 25 00:59:59 CET 2014 International Filing Date: Sat Jun 14 01:59:59 CEST 2014
IPC: C07D 403/12
C07D 401/12
A61K 31/506
A61K 31/4439
A61K 31/497
A61K 31/501
A61K 31/5377
A61P 29/00
A61P 35/00
A61P 25/00
A61P 37/02
A61P 9/10
A61P 9/00
A61P 31/00
A61P 7/08
Applicants: SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO., LTD
上海汇伦生命科技有限公司
Inventors: FAN, Xing
樊兴
QIN, Jihong
秦继红
Title: BENZIMIDAZOLE-2-PIPERAZINE HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD AND USE THEREOF
Abstract:
Disclosed are a benzimidazole-2-piperazine heterocyclic derivative, preparation method and medical use thereof. Particularly disclosed are a new benzimidazole-2-piperazine heterocyclic derivative as represented by general formula (I), preparation method thereof, pharmaceutical composition comprising the same, and use of the derivative as a therapeutic agent, particularly as a poly (ADP-ribose) polymerase (PARP) inhibitor.