WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2014201206) BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/201206    International Application No.:    PCT/US2014/042055
Publication Date: 18.12.2014 International Filing Date: 12.06.2014
IPC:
C07D 403/12 (2006.01), C07D 413/14 (2006.01), C07D 215/36 (2006.01), C07D 413/12 (2006.01), C07D 241/44 (2006.01), C07D 417/12 (2006.01), A61K 31/4704 (2006.01), A61P 29/00 (2006.01)
Applicants: AMGEN INC. [US/US]; One Amgen Center Dr. Thousand Oaks, California 91320 (US)
Inventors: WEISS, Matthew; (US).
BOEZIO, Alessandro; (US).
BOEZIO, Christiane; (US).
BUTLER, John R.; (US).
CHU-MOYER, Margaret Yuhua; (US).
DIMAURO, Erin F.; (US).
DINEEN, Thomas; (US).
GRACEFFA, Russell; (US).
GUZMAN-PEREZ, Angel; (US).
HUANG, Hongbin; (US).
KREIMAN, Charles; (US).
LA, Daniel; (US).
MARX, Isaac E.; (US).
MILGRIM, Benjamin Charles; (US).
NGUYEN, Hanh Nho; (US).
PETERSON, Emily; (US).
ROMERO, Karina; (US).
SPARLING, Brian; (US)
Agent: REDDY, G. Prabhakar; (US)
Priority Data:
61/834,273 12.06.2013 US
61/983,958 24.04.2014 US
Title (EN) BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS
(FR) COMPOSÉS DE SULFONAMIDES BICYCLIQUES UTILISÉS EN TANT QU'INHIBITEURS DU CANAL SODIQUE
Abstract: front page image
(EN)The present invention provides compounds of Formula I, and pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders and itch. Also provided are pharmaceutical compositions containing compounds of the present invention.
(FR)La présente invention concerne des composés de formule (I), et des sels pharmaceutiquement acceptables de ceux-ci, lesquels sont des inhibiteurs de canaux sodiques sensibles à la tension, en particulier, Nav1.7. Ces composés sont utiles pour le traitement de maladies associées à l'activité de canaux sodiques, telles que les troubles de la douleur et la gale. L'invention concerne également des compositions pharmaceutiques contenant des composés de ladite présente invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)