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1. (WO2014201202) RNA INTERFERENCE-BASED THERAPEUTIC AGAINST ANTHRAX

Pub. No.:    WO/2014/201202    International Application No.:    PCT/US2014/042047
Publication Date: Fri Dec 19 00:59:59 CET 2014 International Filing Date: Fri Jun 13 01:59:59 CEST 2014
IPC: A61K 48/00
A61K 39/395
A61P 31/04
C12N 15/00
C07K 16/28
Applicants: TEXAS TECH UNIVERSITY SYSTEM
Inventors: ZENG, Mingtao
AREVALO, Maria, T.
Title: RNA INTERFERENCE-BASED THERAPEUTIC AGAINST ANTHRAX
Abstract:
The present invention includes siRNAs and antibodies that block the interaction between TEM8 and/or CMG2 cell surface proteins and anthrax toxin and methods of treating anthrax exposure with the same.