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Machine translation
1. (WO2014201173) BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/201173    International Application No.:    PCT/US2014/041998
Publication Date: 18.12.2014 International Filing Date: 11.06.2014
IPC:
C07D 403/12 (2006.01), C07D 413/14 (2006.01), C07D 215/36 (2006.01), C07D 413/12 (2006.01), C07D 241/44 (2006.01), C07D 417/12 (2006.01), A61K 31/4704 (2006.01), A61P 29/00 (2006.01)
Applicants: AMGEN INC. [US/US]; One Amgen Center Dr. Thousand Oaks, California 91320 (US)
Inventors: WEISS, Matthew; (US).
DIMAURO, Erin F.; (US).
DINEEN, Thomas; (US).
GRACEFFA, Russell; (US).
GUZMAN-PEREZ, Angel; (US).
HUANG, Hongbin; (US).
KREIMAN, Charles; (US).
MARX, Isaac E.; (US).
NGUYEN, Hanh Nho; (US).
PETERSON, Emily; (US).
DEAK, Holly L.; (US)
Agent: REDDY, G. Prabhakar; (US)
Priority Data:
61/834,273 12.06.2013 US
61/983,958 24.04.2014 US
Title (EN) BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS
(FR) COMPOSÉS DE SULFONAMIDE BICYCLIQUES UTILISÉS EN TANT QU'INHIBITEURS DES CANAUX SODIQUES
Abstract: front page image
(EN)The present invention provides compounds of Formula I or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.
(FR)La présente invention concerne des composés représentés par la formule I, ou leurs sels pharmaceutiquement acceptables, qui sont des inhibiteurs de canaux sodiques sensibles à la tension, en particulier Nav1,7. Lesdits composés sont utiles pour le traitement de maladies pouvant être traitées par inhibition de canaux sodiques, comme les troubles de la douleur. L'invention concerne également des compositions pharmaceutiques contenant les composés de la présente invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)