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1. (WO2014200885) PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/200885 International Application No.: PCT/US2014/041472
Publication Date: 18.12.2014 International Filing Date: 09.06.2014
IPC:
C07D 487/04 (2006.01) ,A61K 31/519 (2006.01) ,A61P 3/10 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
Applicants:
PLAYER, Mark R. [US/US]; US (US)
MEEGALLA, Sanath K. [US/US]; US (US)
ILLIG, Carl R. [US/US]; US (US)
CHEN, Jinsheng [US/US]; US (US)
WILSON, Kenneth J. [US/CR]; CR (US)
LEE, Yu-Kai [US/US]; US (US)
PARKS, Daniel J. [US/US]; US (US)
HUANG, Hui [US/US]; US (US)
PATEL, Sharmila [US/US]; US (US)
JANSSEN PHARMACEUTICA NV [BE/BE]; Turnhoutseweg 30 B-2340 Beerse, BE
LU, Tianbao [US/US]; US (US)
Inventors:
PLAYER, Mark R.; US
MEEGALLA, Sanath K.; US
ILLIG, Carl R.; US
CHEN, Jinsheng; US
WILSON, Kenneth J.; CR
LEE, Yu-Kai; US
PARKS, Daniel J.; US
HUANG, Hui; US
PATEL, Sharmila; US
Agent:
PLANTZ, Bernard F.; US
Priority Data:
61/833,49511.06.2013US
Title (EN) PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES
(FR) INHIBITEURS DE PDE10A DANS LE TRAITEMENT DU DIABÈTE DE TYPE II
Abstract:
(EN) Disclosed are compounds, compositions and methods for treating Type II diabetes. Such compounds are represented by Formula (I) as follows: wherein R1, R2, L, and Q are defined herein.
(FR) L'invention concerne des composés, des compositions et des méthodes de traitement du diabète de type II. Ces composés sont représentés par la formule (I) comme suit : R1, R2, L, et Q sont tels que définis dans la demande.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)