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1. (WO2014200431) METAMATERIAL DEVICE AND USES THEREOF

Pub. No.:    WO/2014/200431    International Application No.:    PCT/SG2014/000264
Publication Date: Fri Dec 19 00:59:59 CET 2014 International Filing Date: Sat Jun 07 01:59:59 CEST 2014
IPC: H01L 27/28
H01L 51/00
B82B 1/00
B82B 3/00
Applicants: NANYANG TECHNOLOGICAL UNIVERSITY
Inventors: XIONG, Qihua
CAO, Cuong
ZHANG, Jun
Title: METAMATERIAL DEVICE AND USES THEREOF
Abstract:
The present invention relates to a logic gate, comprising a metamaterial surface enhanced Raman scattering (MetaSERS) sensor, comprising (a) alphabetical metamaterials in the form of split ring resonators operating in the wavelength range of from 560 to 2200 nm; and (b) a guanine (G) and thymine (T)-rich oligonucleotide that can, upon presence of potassium cations (K+), fold into a G-quadruplex structure, and in presence of Hg2+, form a T-Hg2+-T hairpin complex that inhibits or disrupts the G-quadruplex structure formed in presence of K+, as well as methods of operating and using such a logic gate.