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1. (WO2014200373) 3-CARBAMOYL-1 -METHYLPYRIDINIUM NITRITE, PROCESS FOR ITS PREPARATION AND ITS USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/200373    International Application No.:    PCT/PL2014/050036
Publication Date: 18.12.2014 International Filing Date: 10.06.2014
IPC:
C07D 213/82 (2006.01), A61K 31/455 (2006.01), A61P 9/10 (2006.01), A61P 7/02 (2006.01), A61P 3/00 (2006.01), A61P 9/12 (2006.01)
Applicants: UNIWERSYTET JAGIELLOŃSKI [PL/PL]; Kraków 24 ul. Gołębia PL-31-007 Kraków (PL)
Inventors: CHŁOPICKI, Stefan; (PL).
PERNAK, Juliusz; (PL).
NIEMCZAK, Michał; (PL).
KRAMKOWSKI, Karol; (PL).
LESZCZYŃSKA, Agnieszka; (PL).
WALCZAK, Maria; (PL)
Agent: CZARNIK, Maciej; Bobrzynskiego 14 PL-30-348 Kraków (PL)
Priority Data:
P.404273 11.06.2013 PL
Title (EN) 3-CARBAMOYL-1 -METHYLPYRIDINIUM NITRITE, PROCESS FOR ITS PREPARATION AND ITS USE
(FR) NITRITE DE 3-CARBAMOYL-1-MÉTHYLPYRIDINIUM, PROCÉDÉ POUR SA PRÉPARATION ET SON UTILISATION
Abstract: front page image
(EN)The invention relates to a novel pyridinium salt comprising an anion in the form of a nitrite and a cation in the form of a 3-carbamoyl-l -methylpyridinium, the process of its preparation and its use for the manufacture of a vascular protective agent for the treatment or prevention of conditions or diseases associated with the dysfunction of vascular endothelium, failure of endothelial synthesis of nitric oxide (NO) and/or failure of endothelial synthesis of prostacyclin (PGI2).
(FR)La présente invention concerne un nouveau sel de pyridinium comprenant un anion sous la forme d'un nitrite et un cation sous la forme d'un 3-carbamoyl-1-méthylpyridinium, le procédé pour sa préparation et son utilisation dans la production d'un agent protecteur vasculaire pour le traitement ou la prévention d'états pathologiques ou de maladies associés au dysfonctionnement de l'endothélium vasculaire, un défaut de synthèse endothéliale de l'oxyde nitrique (NO) et/ou un défaut de synthèse endothéliale de la prostacycline (PGI2).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)