Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2014200091) AΒ PEPTIDE OXIDANT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/200091 International Application No.: PCT/JP2014/065749
Publication Date: 18.12.2014 International Filing Date: 13.06.2014
IPC:
C07K 14/47 (2006.01) ,A61K 38/00 (2006.01) ,A61K 45/00 (2006.01) ,A61P 25/28 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
28
for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants:
国立研究開発法人科学技術振興機構 JAPAN SCIENCE AND TECHNOLOGY AGENCY [JP/JP]; 埼玉県川口市本町4丁目1番8号 1-8, Honcho 4-chome, Kawaguchi-shi, Saitama 3320012, JP
Inventors:
金井 求 KANAI, Motomu; JP
相馬 洋平 SOMA, Yohei; JP
谷口 敦彦 TANIGUCHI, Atsuhiko; JP
佐々木 大輔 SASAKI, Daisuke; JP
Agent:
特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE; 東京都中央区日本橋人形町1丁目3番8号 沢の鶴人形町ビル Sawanotsuru Ningyocho Bldg., 1-3-8, Nihonbashi Ningyocho, Chuo-ku, Tokyo 1030013, JP
Priority Data:
2013-12579714.06.2013JP
2013-23962220.11.2013JP
Title (EN) AΒ PEPTIDE OXIDANT
(FR) OXYDANT DU PEPTIDE AΒ
(JA) Aβペプチド酸化体
Abstract:
(EN)  Provided are an agent for inhibiting the aggregation and an agent for lowering the toxicity of Aβ peptide, as well as an agent for the prevention and treatment of Alzheimer's disease. An Aβ oxidant that oxidizes one or more amino acid residues that constitute Aβ peptide (excluding an Aβ oxidant that oxidizes only Met).
(FR)  Cette invention concerne un agent pour inhiber l'agrégation et un agent pour abaisser la toxicité du peptide Aβ, ainsi qu'un agent pour prévenir et traiter la maladie d'Alzheimer. L'oxydant Aβ selon l'invention oxyde un ou plusieurs des résidus acides aminés qui constituent le peptide Aβ (exclusion faite d'un oxydant Aβ qui n'oxyde que Met).
(JA)  Aβペプチドの凝集抑制剤及び毒性低減剤、並びにアルツハイマー病の予防治療剤の提供。 Aβペプチドを構成する一以上のアミノ酸残基が酸化されているAβペプチド酸化体(Metのみが酸化されているAβペプチド酸化体を除く)。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)