Search International and National Patent Collections

1. (WO2014200054) METHOD FOR DETERMINING DOSAGE OF ERYTHROPOIESIS-STIMULATING AGENT

Pub. No.:    WO/2014/200054    International Application No.:    PCT/JP2014/065571
Publication Date: Fri Dec 19 00:59:59 CET 2014 International Filing Date: Fri Jun 13 01:59:59 CEST 2014
IPC: G01N 33/72
Applicants: NIPRO CORPORATION
ニプロ株式会社
Inventors: SHINZATO, Toru
新里 徹
MARUYAMA, Yasuyo
丸山 泰代
UENO, Fumihiko
上野 史彦
Title: METHOD FOR DETERMINING DOSAGE OF ERYTHROPOIESIS-STIMULATING AGENT
Abstract:
Provided is a method for determining the dosage of an ESA, whereby the hemoglobin concentration in the blood may be consistently maintained at a target value, and the range of fluctuation with respect to the target hemoglobin concentration may be reduced. A target hemoglobin concentration in the blood is established; a target hemoglobin production rate for achieving the target hemoglobin concentration is calculated, as well as calculating, from the relationship of the hemoglobin production rate and the ESA concentration, an ESA concentration in the blood for achieving the target hemoglobin production rate; and an ESA dosage for achieving the ESA concentration in the blood is calculated from the relationship of the ESA concentration and the ESA dosage, to determine an ESA dosage for achieving the target hemoglobin concentration.