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1. (WO2014199364) SEMAPHORIN 3A FOR TREATMENT AND PROGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/199364 International Application No.: PCT/IL2013/050504
Publication Date: 18.12.2014 International Filing Date: 13.06.2013
IPC:
A61K 38/17 (2006.01) ,G01N 33/53 (2006.01)
Applicants: MEDICAL RESEARCH & DEVELOPMENT FUND FOR HEALTH SERVICES BNAI ZION MEDICAL CENTER[IL/IL]; 47 Golomb St. 31048 Haifa, IL
Inventors: VADASZ, Zahava; IL
TOUBI, Elias; IL
Agent: WEBB , Cynthia; Webb & Co. P.O. Box 2189 76121 Rehovot, IL
Priority Data:
Title (EN) SEMAPHORIN 3A FOR TREATMENT AND PROGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
(FR) SÉMPHORINE 3A POUR LE TRAITEMENT ET LE PRONOSTIC DU LUPUS ÉRYTHÉMATEUX SYSTÉMIQUE
Abstract:
(EN) The present invention relates to Semaphorin 3A (Sema3A) and its use in treatment and prognosis of Systemic Lupus Erythematosus (SLE). The present invention provides, inter-alia, methods of treating a subject afflicted with SLE, comprising administering to the subject a pharmaceutical composition comprising isolated Sema3A. The present invention further provides methods for prognosis of SLE, comprising measuring Sema3A serum concentration in a subject in need thereof.
(FR) La présente invention concerne la sémaphorine A3 (Sema3A) et son utilisation dans le traitement et le pronostic du lupus érythémateux systémique (SLE). La présente invention concerne, entre autres, des procédés de traitement d'un sujet atteint de SLE et comprenant l'administration au dit sujet d'une composition pharmaceutique comprenant de la Sema3A isolée. La présente invention concerne en outre des procédés de pronostic du SLE comprenant la mesure de la concentration sérique de Sema3A chez un sujet le nécessitant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)