Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2014198902) IMPLANTABLE MATERIAL GRAFTED WITH A CELL ANTIPROLIFERATIVE AND/OR ANTIBACTERIAL FILM SYNTHETIZED FROM A BIFUNCTIONAL MOLECULE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2014/198902 International Application No.: PCT/EP2014/062392
Publication Date: 18.12.2014 International Filing Date: 13.06.2014
IPC:
A61L 27/34 (2006.01) ,C07C 309/17 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
28
Materials for coating prostheses
34
Macromolecular materials
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
309
Sulfonic acids; Halides, esters, or anhydrides thereof
01
Sulfonic acids
02
having sulfo groups bound to acyclic carbon atoms
03
of an acyclic saturated carbon skeleton
17
containing carboxyl groups bound to the carbon skeleton
Applicants:
BIOWINTECH [FR/FR]; 60 rue Saint-André-des-Arts F-75006 Paris, FR
COMMISSARIAT À L’ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA) [FR/FR]; Bâtiment Le Ponant D 25 rue Leblanc F-75015 Paris, FR
Inventors:
DENIAU, Guy; FR
ZOBRIST, Cédric; FR
OUDIN, Maxime; FR
DAVID, Laurent; FR
Agent:
ICOSA; 83 avenue Denfert-Rochereau F-75014 Paris, FR
Priority Data:
13172180.514.06.2013EP
Title (EN) IMPLANTABLE MATERIAL GRAFTED WITH A CELL ANTIPROLIFERATIVE AND/OR ANTIBACTERIAL FILM SYNTHETIZED FROM A BIFUNCTIONAL MOLECULE
(FR) MATÉRIAU IMPLANTABLE GREFFÉ D'UN FILM CELLULAIRE ANTIPROLIFÉRATIF ET/OU ANTIBACTÉRIEN SYNTHÉTISÉ À PARTIR D'UNE MOLÉCULE BIFONCTIONNELLE
Abstract:
(EN) The present invention relates to an implantable material having at least one external surface grafted with a film comprising carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on said external surface by radical reaction of a bifunctional adhesion primer of Formula (I) or by radical reaction of an adhesion primer and a bifunctional polymerizable monomer of Formula (II). The invention also relates to a process for directly synthesizing and grafting of a film according to the invention onto at least one external surface of an implantable material. The invention further relates to the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device. The invention also relates to compounds of Formula (I) and Formula (II).
(FR) La présente invention concerne un matériau implantable ayant au moins une surface extérieure greffée d'un film comprenant des fonctions carboxylate et sulfonate, le film étant simultanément synthétisé et greffé directement sur ladite surface extérieure par réaction radicalaire d'un apprêt d'adhérence bi-fonctionnel de formule (I) ou par réaction d'un apprêt d'adhérence et d'un monomère polymérisable bi-fonctionnel de formule (II). L'invention concerne aussi un procédé pour directement synthétiser et greffer un film selon l'invention sur au moins une surface extérieure d'un matériau implantable. L'invention concerne également l'utilisation d'un matériau implantable greffé pour la fabrication d'un dispositif médical implantable antiprolifératif et/ou antibactérien. L'invention concerne en outre des composés de formule (I) et de formule (II).
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)