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1. (WO2014198849) ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS

Pub. No.:    WO/2014/198849    International Application No.:    PCT/EP2014/062281
Publication Date: Fri Dec 19 00:59:59 CET 2014 International Filing Date: Fri Jun 13 01:59:59 CEST 2014
IPC: C07D 277/56
A61K 31/426
A61P 31/00
Applicants: ANTABIO SAS
Inventors: LEMONNIER, Marc
DAVIES, David
PALLIN, Thomas David
Title: ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS
Abstract:
Compounds of general formula (I), wherein R1, R11, Y, R2, n and A are as defined herein are useful as inhibitors or metallo-β-lactamase (MBL) enzymes and can be used for reducing or removing antibiotic resistance in bacteria.