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1. (WO2014198848) COMPOUNDS

Pub. No.:    WO/2014/198848    International Application No.:    PCT/EP2014/062280
Publication Date: Fri Dec 19 00:59:59 CET 2014 International Filing Date: Fri Jun 13 01:59:59 CEST 2014
IPC: C07D 471/04
A61P 35/00
A61K 21/437
Applicants: LYTIX BIOPHARMA AS
Inventors: STENSEN, Wenche
SCHEVENELS, Florian
MARKO, Istvan, E.
SVENDSEN, John, Sigurd, Mjøen
Title: COMPOUNDS
Abstract:
The present invention provides a compound incorporating a group of formula (I) wherein: 1 of X, Y and Z is nitrogen and the other 2 are carbon; R" is hydrogen, methyl, ethyl or propyl; and W represents hydrogen, carbon, nitrogen, oxygen or sulphur; or incorporating a salt, hydrate or solvate of a group of formula (I); as well as therapeutic uses of these compounds, in particular as inhibitors of protein kinase activity and in the treatment of inflammation, inflammatory conditions and cancer.