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1. (WO2014198683) COMPOSITIONS COMPRISING CROSS-LINKED HYALURONIC ACID AND CYCLODEXTRIN

Pub. No.:    WO/2014/198683    International Application No.:    PCT/EP2014/061942
Publication Date: Fri Dec 19 00:59:59 CET 2014 International Filing Date: Tue Jun 10 01:59:59 CEST 2014
IPC: A61K 31/724
A61K 31/728
A61K 31/07
A61K 8/73
A61Q 19/00
C08B 37/00
Applicants: GALDERMA S.A.
Inventors: BOITEAU, Jean-Guy
Title: COMPOSITIONS COMPRISING CROSS-LINKED HYALURONIC ACID AND CYCLODEXTRIN
Abstract:
The present invention relates to a hyaluronic acid composition comprising a hyaluronic acid and one or more cyclodextrin molecules covalently bound to said hyaluronic acid via a bi- or polyfunctional crosslinking agent, wherein the covalent bonds between said hyaluronic acid and said crosslinking agent and between said crosslinking agent and said cyclodextrin molecules are ether bonds. The present invention relates to medical and cosmetic (non-medical) uses of such compositions further comprising a pharmaceutical or medical agent and to a method of preparing a slow release formulation.